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PLoS ONEVolume 10, Issue 4, 27 April 2015, Article number e0124257

An empirical analysis of primary and secondary pharmaceutical patents in Chile(Article)(Open Access)

  • Abud, M.J.,
  • Hall, B.,
  • Helmers, C.
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  • aSchool of International and Public Affairs, Columbia University, New York, United States
  • bDepartment of Economics, University of California, Berkeley, CA, United States
  • cUNUMERIT, University of Maastricht, Maastricht, Netherlands
  • dDepartment of Economics, Santa Clara University, Santa Clara, CA, United States

Abstract

We analyze the patent filing strategies of foreign pharmaceutical companies in Chile distinguishing between "primary" (active ingredient) and "secondary" patents (patents on modified compounds, formulations, dosages, particular medical uses, etc.). There is prior evidence that secondary patents are used by pharmaceutical originator companies in the U. S. and Europe to extend patent protection on drugs in length and breadth. Using a novel dataset that comprises all drugs registered in Chile between 1991 and 2010 as well as the corresponding patents and trademarks, we find evidence that foreign originator companies pursue similar strategies in Chile. We find a primary to secondary patents ratio of 1:4 at the drug-level, which is comparable to the available evidence for Europe; most secondary patents are filed over several years following the original primary patent and after the protected active ingredient has obtained market approval in Chile. This points toward effective patent term extensions through secondary patents. Secondary patents dominate "older" therapeutic classes like anti-ulcer and anti-depressants. In contrast, newer areas like anti-virals and anti-neoplastics (anti-cancer) have a much larger share of primary patents. © 2015 Abud et al.

Indexed keywords

EMTREE medical terms:ArticleChiledeveloping countrydrug approvaldrug identificationdrug industrydrug informationdrug legislationdrug marketingpatentprimary patentregistrationsecondary patentdrug industryhumanmedicinal chemistry
EMTREE drug terms:drug
MeSH:Chemistry, PharmaceuticalChileDrug IndustryHumansPatents as TopicPharmaceutical Preparations

Chemicals and CAS Registry Numbers:

Pharmaceutical Preparations

  • ISSN: 19326203
  • CODEN: POLNC
  • Source Type: Journal
  • Original language: English
  • DOI: 10.1371/journal.pone.0124257
  • PubMed ID: 25915050
  • Document Type: Article
  • Publisher: Public Library of Science


© Copyright 2015 Elsevier B.V., All rights reserved.

Cited by 8 documents

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(2020) Journal of International Business Studies
View details of all 8 citations
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