

The isolation of 11(13)-dehydrocriolin [a germacranolide also known as 11(13)-dehydroivaxillin], 2α-hydroxyalantolactone, 4α,5α-epoxy-10α,14-H-inuviscolide (the major component) and carabrone from the aerial parts of Inula helenium is reported. The first two lactones were isolated for the first time from this plant. © 1989.
Acknowledgements-Tins work was supported m part by the Serblan Repubhc Research Fund We thank Dr A. Romo de Vlvar, Dr J S Calderbn (both from Instltuto de QtnmIca de la Umversldad Naclonal Autcinoma de MCXICO) and Dr M Maruyama (Mlyagi Umverslty oTEducatton, Japan) for kmdfy supplymg us with IR and ‘H NMR spectra oflactone 3 We also wish to acknowledge our gratitude to Professor J L Markley for the use of the NMR faohty at the Department of Blochermstry, Umverslty of Wlsconsm, Madison, U S A
Vajs, V.; Institutes for Chemistry and Physical Chemistry, Faculty of Science, University of Belgrade, Studentski trg 16, P.0, Box 550,
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