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Journal of Pharmaceutical and Biomedical AnalysisVolume 11, Issue 3, March 1993, Pages 207-210

Coulometric determination of some antiasthmatics(Article)

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  • Department of Organic Chemistry, Faculty of Pharmacy, University of Belgrade, Belgrade

Abstract

A simple and rapid method for the assay of microquantities of fenoterol hydrobromide, orciprenaline sulphate and terbutaline sulphate in pure state and various pharmaceutical formulations, is presented. The method is based on the coulometric titration of the investigated compounds with electrogenerated chlorine in the presence of methyl orange as indicator. The method requires a simple apparatus and gives accurate and reproducible results. © 1993.

Author keywords

antiasthmaticsChlorocoulometric titrationdrug analysisfenoterolorciprenalineterbutaline.

Indexed keywords

EMTREE drug terms:antiarrhythmic agentfenoterolorciprenalineterbutaline
EMTREE medical terms:chemical analysisconference papercoulometrydrug analysisdrug determination
MeSH:AerosolsChemistry, PharmaceuticalDosage FormsElectrodesFenoterolOrciprenalineTerbutaline

Chemicals and CAS Registry Numbers:

fenoterol, 13392-18-2, 1944-12-3; orciprenaline, 586-06-1, 5874-97-5; terbutaline, 23031-25-6;

Aerosols; Dosage Forms; Fenoterol, 13392-18-2; Orciprenaline, 586-06-1; Terbutaline, 23031-25-6

Drug tradename:

  • alupent, zdravlje pharma and chemical works, Yugoslavia,
  • bricanyl, bosnalijek, Yugoslavia,
  • terbutaline, bosnalijek, Yugoslavia

Manufacturers:

Drug manufacturer:

bosnalijek, Yugoslavia;

zdravlje pharma and chemical works, Yugoslavia

  • ISSN: 07317085
  • CODEN: JPBAD
  • Source Type: Journal
  • Original language: English
  • DOI: 10.1016/0731-7085(93)80198-A
  • PubMed ID: 8518319
  • Document Type: Article

  Nikolic, K.; Department of Organic Chemistry, Faculty of Pharmacy, University of Belgrade,
© Copyright 2014 Elsevier B.V., All rights reserved.

Cited by 13 documents

Zamuner, M.L.M. , Carrion, R.C.E. , Magalhães, J.F.
Spectrophotometric determination of fenoterol hydrobromide in pharmaceutical preparations | Determinação espectrofotométrica do bromidrato de fenoterol em preparações farmacêuticas
(2008) Revista Brasileira de Ciencias Farmaceuticas/Brazilian Journal of Pharmaceutical Sciences
El Nashar, R.M.
Determination of Orciprenaline using a flow injection analysis system with sequential potentiometric and spectrophotometric detection
(2008) Analytical Letters
Eid, M.
Spectrofluorimetric determination of fenoterol in pharmaceuticals
(2007) Journal of the Chinese Chemical Society
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