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Journal of Molecular Catalysis A: ChemicalVolume 170, Issue 1-2, 14 May 2001, Pages 267-269

Vitamin B12-catalyzed conversion of some γ- and δ-bromoalkanols to polyhydroxy alkanols(Letter)

  • Petrović, Z.,
  • Mojsilović, B.,
  • Bugarčić, Z.M.
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  • Department of Chemistry, Faculty of Science, Radoja Domanovica 12, 34000 Kragujevac, Serbia

Abstract

Vitamin B12-catalyzed allylic dimerization of some γ- and δ-bromoalkanols with activated Zn-dust in mixture ethanol/water (1:1) has been studied. Investigated bromoalkanols were prepared from corresponding tertiary Δ4- and Δ5-alkenols by means of benzeneselenyl bromide and subjected to chemical reduction with vitamin B12. All investigated bromoalkanols, after dehydrobromination, underwent to oxidative allylic coupling and hydratation in the presence of protic solvents to give predominantly polyhydroxy alkanols. © 2001 Elsevier Science B.V.

Author keywords

Allylic couplingBromoalkanolsDehydrobrominationHydratationPolyhydroxy alkanolsVitamin B12

Indexed keywords

Engineering controlled terms:CatalysisReaction kineticsReductionSolventsVitaminsZinc
Engineering uncontrolled terms:Alkanols
Engineering main heading:Alcohols
EMTREE drug terms:alcohol derivativebromine derivativecyanocobalaminpolyol
EMTREE medical terms:articlebrominationcatalysisdimerizationreaction analysissynthesis
  • ISSN: 13811169
  • Source Type: Journal
  • Original language: English
  • DOI: 10.1016/S1381-1169(00)00557-4
  • Document Type: Letter


© Copyright 2018 Elsevier B.V., All rights reserved.

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