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Analytical LettersVolume 25, Issue 9, 1 September 1992, Pages 1687-1692

Spectrophotometric Determination of Methandienone in Tablets Using 1.4-Dihydrazinophthalazine(Article)

  • Zivanov Stakic, D.,
  • Agbaba, D.,
  • Vladimirov, S.
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  • Faculty of Pharmacy, Department of Pharmaceutical, Chemistry,Vojvode Stepe 450, P.O.Box 146, 11000 Belgrade, Serbia

Abstract

A simple and sensitive method for the determination of methandienone in tablets using 1.4-dihydrazinophthalazine as the reagent is presented. The yellow coloured dihydralazinhydrazone shows the maximum at 401 nm and molar absorptivity of 1.5x104 1 mol-1cm-1. Beer's law is obeyed up to 16 μ g/ml methandienone. The method applied for the assay of methandienone in dosage form gave precise and reproducible results; recovery was 98.57. and relative standard deviation was 1.57%. © 1992, Taylor & Francis Group, LLC. All rights reserved.

Author keywords

methandienone,colorimetry,1.4-dihydrazinophthalazine,NerobolR tablets
  • ISSN: 00032719
  • Source Type: Journal
  • Original language: English
  • DOI: 10.1080/00032719208018243
  • Document Type: Article


© Copyright 2016 Elsevier B.V., All rights reserved.

Cited by 2 documents

Bao, J. , Zhang, Q. , Huang, W.
Determination of Metandienone using molecularly Imprinted based Electrochemical Sensor in human urine
(2022) International Journal of Electrochemical Science
Vladimirov, S. , Čudina, O. , Agbaba, D.
Spectrophotometric determination of desoximetasone in ointment using 1,4-dihydrazinophthalazine
(1996) Journal of Pharmaceutical and Biomedical Analysis
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