Chemical structure and antifungal activity of mint essential oil components(Article)(Open Access)
- aFaculty of Technology, University of Novi Sad, Bulevar cara Lazara 1, Novi Sad, 21000, Serbia
- bInstitute of Food Technology, University of Novi Sad, Bulevar cara Lazara 1, Novi Sad, 21000, Serbia
- cFaculty of Science, Department of Geography, Tourism and Hotel Management, University of Novi Sad, Trg Dositeja Obradovića 3, Novi Sad, 21000, Serbia
- dEngineering Department, Institute of General and Physical Chemistry, University of Belgrade, Studentski Trg 12-16, Belgrade, 11000, Serbia
- eColledge of Management and Business Communications, Mitropolita Stratimirovića 110, Sremski-Karlovci, 21205, Serbia
Abstract
The objective of this research was to determine chemical composition and to evaluate the antifungal activity of essential oil of Mentha piperita. By the application of GC/MS analysis of essential mint oil, 27 components were identified. The major components were menthol (39.9 %), menton (23.51 %), menthyl acetate (7.29 %), 1.8-cineol (5.96 %), isomenton (5.24 %), isomenthol (3.17 %), trans-caryophyllene (2.88 %), limonene (2.14 %), pulegon (1.38 %), beta-pinene (1.14 %) and piperiton (1.03 %). The quantitative structure- retention relationship (QSRR) was employed to predict the retention time (RT) of Mentha piperita essential oil compounds obtained in GC/MS analysis, using twelve molecular descriptors selected by genetic algorithm. The selected descriptors were used, as inputs of an artificial neural network, to build an RT predictive QSRR model. The coefficient of determination was 0.983, during training cycle, indicating that this model could be used for prediction of RT values for essential oil compounds in Mentha piperita essential oil extracts. Essential oil of Mentha piperita showed antifungal activity on all tested isolates in the minimal inhibitory concentration range of 0.2-1.7 μl/ml and a minimal fungicidal concentration (MFC) range of 1.7-454.5 μl/ml. The most powerful antifungal activity of mint was observed in C. cladosporioides of MFC value 1.7 μl/ml. P. aurantiogriseum showed the lowest sensitivity of MFC value 454.5 μl/ml. © 2020 Serbian Chemical Society. All rights reserved.
Funding details
| Funding sponsor | Funding number | Acronym |
|---|---|---|
| 31029 |
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1
Acknowledgement. The results are part of the research from the Project No. 31029 financed by the Ministry of Education, Science and Technological Development of the Republic of Serbia.
- ISSN: 03525139
- CODEN: JSCSE
- Source Type: Journal
- Original language: English
- DOI: 10.2298/JSC191210017P
- Document Type: Article
- Publisher: Serbian Chemical Society
Plavšić, D.V.; Faculty of Technology, University of Novi Sad, Bulevar cara Lazara 1, Novi Sad, Serbia;
© Copyright 2021 Elsevier B.V., All rights reserved.
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