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Annals of Biomedical EngineeringVolume 48, Issue 12, December 2020, Pages 2705-2706

Abrupt Deterioration of COVID-19 Patients and Spreading of SARS COV-2 Virions in the Lungs(Letter)(Open Access)

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  • aFaculty of Engineering, University of Kragujevac, Sestre Janjic 6, Kragujevac, 34000, Serbia
  • bBiomedical Research and Development Center for Bioengineering (BIOIRC), Prvoslava Stojanovica 6, Kragujevac, 34000, Serbia
  • cDepartment Respiratory Medicine, Nara Medical University, Shijo 840, Kashihara, Nara 634-8521, Japan
  • dTsuda Lung Research, Shrewsbury, MA 01545, United States

Abstract

A unique feature of COVID-19 interstitial pneumonia is an abrupt progression to respiratory failure. Our calculation shows that this abrupt deteriorate may be caused by a sudden shift in the spread of virus-laden bioaerosols through the airways to many different regions of the lungs from the initial site of infection. © 2020, Biomedical Engineering Society.

Indexed keywords

Engineering controlled terms:DiseasesViruses
Engineering uncontrolled termsBioaerosolsRespiratory failureSpread of virusUnique features
Engineering main heading:Deterioration
EMTREE medical terms:breathingcomputer assisted tomographycoronavirus disease 2019cytokine stormdisease coursedisease severityground glass opacityhumanimmune responseinterstitial pneumoniaLetterlunglung edemalung lesionlymph flownonhumanpriority journalrespiratory airflowrespiratory failureSevere acute respiratory syndrome coronavirus 2virionvirus transmissionbiological modelmetabolismpathologyvirion
MeSH:COVID-19HumansLungModels, BiologicalSARS-CoV-2Virion
  • ISSN: 00906964
  • CODEN: ABMEC
  • Source Type: Journal
  • Original language: English
  • DOI: 10.1007/s10439-020-02676-w
  • PubMed ID: 33140243
  • Document Type: Letter
  • Publisher: Springer

  Filipovic, N.; Faculty of Engineering, University of Kragujevac, Sestre Janjic 6, Kragujevac, Serbia;
© Copyright 2020 Elsevier B.V., All rights reserved.

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