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BIBE 2021 - 21st IEEE International Conference on BioInformatics and BioEngineering, Proceedings202121st IEEE International Conference on BioInformatics and BioEngineering, BIBE 2021; University of KragujevacKragujevac; Serbia; 25 October 2021 through 27 October 2021; Category numberCFP21266-ART; Code 175551

Determination of VEGF and CXCR4 in Tumor and Peritumoral Tissue of Patients with Breast Cancer as a Predictive Factor(Conference Paper)

  • Cvetkovic, D.,
  • Cvetkovic, A.,
  • Nikodijevic, D.,
  • Jovankic, J.,
  • Milutinovic, M.,
  • Stojic, V.,
  • Zdravkovic, N.,
  • Mltrovic, S.
  Save all to author list
  • University of Kragujevac, Institute for Information Technologies, Departmentof Science, Serbia

Abstract

Despite the obvious progress in the field of diagnosis and therapy, further measures are needed to increase the effectiveness of treatment and reduce morbidity and mortality from breast cancer. An immunofluorescence method was used to determine the protein expression of VEGF and CXCR-4 in tumor and peritumoral tissue. Peritumoral tissue is not only a passive factor, but actively participates in the process of tumor growth and development, as well as in the processes of recurrence and metastasis. Markers of neoangiogenesis in tumor and peritumoral tissue such as protein expression of VEGF and CXCR-4 receptors may serve as reliable predictors of disease outcome in breast cancer patients, which may provide useful suggestions in treatment choices. © 2021 IEEE.

Author keywords

breast cancerperitumoral tissuepredictive factor introductionvegf cxcr-4

Indexed keywords

Engineering controlled terms:DiagnosisDiseasesPatient treatmentProteins
Engineering uncontrolled termsBreast CancerGrowth and developmentImmunofluorescence methodsPeritumoral tissuePredictive factor introductionPredictive factorsProtein expressionsTumor developmentTumor growthVegf cxcr-4
Engineering main heading:Tumors

Funding details

Funding sponsor Funding number Acronym
451-03-9/2021-14/200378
Ministarstvo Prosvete, Nauke i Tehnološkog Razvoja451-03-9/2021-14/200107MPNTR

  • 1

    The research was funded by Serbian Ministry of Education, Science, and Technological Development, grant [451-03-9/2021-14/200107 Faculty of Engineering, University of Kragujevac and 451-03-9/2021-14/200378 University of Kragujevac, Institute for Information Technologies, Kragujevac].

  • ISBN: 978-166544261-9
  • Source Type: Conference Proceeding
  • Original language: English
  • DOI: 10.1109/BIBE52308.2021.9635306
  • Document Type: Conference Paper
  • Sponsors: Institute of Electrical and Electronic Engineers (IEEE),Ministry of Education, Science and Technological Development of the Republic of Serbia,Research and Development Center for Bioengineering BioIRC,University of Kragujevac
  • Publisher: Institute of Electrical and Electronics Engineers Inc.


© Copyright 2022 Elsevier B.V., All rights reserved.

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