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This study investigated the interaction of groundwater flow and foundation piles located in the vicinity of the Danube River. The piles represent an obstacle to the groundwater flow, causing a backwater effect upstream whilst increasing the local flow velocity. On the other hand, a high flow velocity around the piles can cause suffusion of the surrounding soil in the long term, thus significantly reducing the shaft resistance of the piles. A 3D model of groundwater flow and its impact on the piles was developed in the software 10.3 package GMS based on MODFLOW 2005. The model was calibrated by comparing the calculated results with the measured values in the control well for different values of the filtration coefficients. In the calibration process, foundation piles were not applied in the model. After the calibration process, the piles were implemented into the model and the underground flow was simulated in the study area for the calibrated year 2006. The impact analysis was carried out by comparing the groundwater level change over time in the pile zone at three control points, in cases with and without the piles, along with the flow net analysis at the piles’ location. The results indicate no influence of the piles on the groundwater flow in the study area, both in terms of critical flow velocities and a possible backwater effect upstream. © 2023 by the authors.