Metal-organic frameworks: synthesis, properties, wound dressing, challenges and scopes in advanced wound dressing(Review)
- aDepartment of Mechanical and Industrial Engineering, Qatar University, Doha, 2713, Qatar
- bBiomedical Research Center, Qatar University, Doha, 2713, Qatar
- cDepartment of Physics, University of Engineering and Technology, Lahore, 39161, Pakistan
- dPolymer Chemistry Laboratory, Department of Chemistry, Quaid-i-Azam University, Islamabad, 45320, Pakistan
- eOral and Maxillofacial Surgery Unit, School of Dental Sciences, Universiti Sains Malaysia, Health Campus, Kubang Kerian Kelantan, Kota Bharu, 16150, Malaysia
- fOral and Maxillofacial Surgery Unit, Hospital Universiti Sains Malaysia, Universiti Sains Malaysia, Health Campus, Kubang Kerian Kelantan, Kota Bharu, 16150, Malaysia
- gFaculty of Technical Sciences, University of Novi Sad, T. D. Obradovica 6, Novi Sad, 21000, Serbia
Abstract
Wound healing is a critical but complex biological process of skin tissue repair and regeneration resulting from various systems working together at the cellular and molecular levels. Quick wound healing and the problems associated with traditional wound repair techniques are being overcome with multifunctional materials. Over time, this research area has drawn significant attention. Metal-organic frameworks (MOFs), owning to their peculiar physicochemical characteristics, are now considered a promising class of well-suited porous materials for wound healing in addition to their other biological applications. This detailed literature review provides an overview of the latest developments in MOFs for wound healing applications. We have discussed the synthesis, essential biomedical properties, wound-healing mechanism, MOF-based dressing materials, and their wound-healing applications. The possible major challenges and limitations of MOFs have been discussed, along with conclusions and future perspectives. This overview of the literature review addresses MOFs-based wound healing from several angles and covers the most current developments in the subject. The readers may discover how the MOFs advanced this discipline by producing more inventive, useful, and successful dressings. It influences the development of future generations of biomaterials for the healing and regeneration of skin wounds. © 2024 IOP Publishing Ltd.
Indexed keywords
| Engineering controlled terms: | Porous materialsRepairTissue regeneration |
|---|---|
| Engineering uncontrolled terms | Anti-bacterial activityBiological processComposites materialInfected woundsLiterature reviewsMetalorganic frameworks (MOFs)PropertyWound dressingsWound healingWound healing applications |
| Engineering main heading: | Organometallics |
| EMTREE drug terms: | biomaterialmetal organic frameworkbiomaterial |
| EMTREE medical terms: | antibacterial activitycomposite materialcontrolled studyhumannonhumanreviewskin injurysynthesistissue repairwound dressingwound healingwound infectionanimalbandagechemistryporosityskin |
| MeSH: | AnimalsBandagesBiocompatible MaterialsHumansMetal-Organic FrameworksPorositySkinWound Healing |
Chemicals and CAS Registry Numbers:
Biocompatible Materials; Metal-Organic Frameworks
Funding details
| Funding sponsor | Funding number | Acronym |
|---|---|---|
| Horizon 2020 Framework Programme See opportunities by H2020 | 872370 | H2020 |
| Horizon 2020 Framework Programme See opportunities by H2020 | H2020 |
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1
We would like to thank the European Union\u2019s Horizon Programme for partly supporting the research project. This project has received funding from the European Union\u2019s Horizon 2020 research and innovation program under Grant Agreement No. 872370.
- ISSN: 17486041
- Source Type: Journal
- Original language: English
- DOI: 10.1088/1748-605X/ad6070
- PubMed ID: 38976990
- Document Type: Review
- Publisher: Institute of Physics
Khan, M.U.A.; Department of Mechanical and Industrial Engineering, Qatar University, Doha, Qatar;
Abdullah, M.F.B.; Oral and Maxillofacial Surgery Unit, School of Dental Sciences, Universiti Sains Malaysia, Health Campus, Kubang Kerian Kelantan, Kota Bharu, Malaysia;
© Copyright 2024 Elsevier B.V., All rights reserved.
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